Endocrine Abstracts

Involutional changes of gonadal function in healthy ageing men are progressive and mostly of modest amplitude with considerable between- subject variability. Albeit some men may remain relatively spared, the occurrence of age-related changes are nevertheless well documented at the population level in both cross-sectional and longitudinal observational studies. These changes affect Sertoli cell function and spermatogenesis as well as Leydig cell function and testosterone (T) pr...